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9780849367335

Biological Regulation of the Chondrocytes

by ;
  • ISBN13:

    9780849367335

  • ISBN10:

    0849367336

  • Format: Hardcover
  • Copyright: 1992-06-16
  • Publisher: CRC Press

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Summary

Biological Regulation of the Chondrocytes provides a comprehensive examination of the various regulations in which cartilaginous cells are involved. The book's introductory chapter provides an overview of the different types of chondrocyte, while following chapters discuss the various biological regulations implicated in chondrocyte functions, especially the modulation of differentiative properties. Chapters 2 and 3 examine the extracellular matrix components, and Chapter 4 discusses the special case of cultured chondrocytes and the usefulness of in vitro approaches. The following three chapters focus on the complex role of cartilaginous growth factors and cytokines (FGF, TGFB, IGF, and IL1) on the modulation of the chondrocyte properties. Chapter 9 discusses the synoviocyte, and the last four chapters examine the biochemical and molecular perturbations that appear during repair, aging, rheumatic disease, and cancer.Biological Regulation of the Chondrocytes will benefit rheumatologists, pharmaceutical researchers, physiologists, connective tissue specialists, and students and other researchers in the osteoarticular field.

Table of Contents

The Different Types of Chondrocytes and Their Function In Vivop. 1
Cartilage Collagensp. 33
Proteoglycan, Hyaluronan, and Noncollagenous Matrix Protein Metabolism by Chondrocytesp. 85
Different Types of Cultured Chondrocytes--The In Vitro Approach to the Study of Biological Regulationp. 105
Roles of Fibroblast Growth Factor and Transforming Factor-[Beta] Families in Cartilage Formationp. 141
Role of IGF in the Regulation of Chondrocytesp. 161
Regulation of Chondrocytes by Cytokinesp. 191
Intercellular Regulation by Synoviocytesp. 205
Articular Cartilage Repair: Potential Role of Growth and Differentiation Factorsp. 227
Regulation of Chondrocytes in Agingp. 237
Regulation of Chondrocytes in Rheumatoid Arthritisp. 275
Regulation of Chondrocytes in Osteoarthrosisp. 295
Regulation of Tumor Derived and Immortalized Chondrocytesp. 321
Indexp. 339
Table of Contents provided by Blackwell. All Rights Reserved.

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