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9780192632913

The Muscular Dystrophies

by
  • ISBN13:

    9780192632913

  • ISBN10:

    0192632914

  • Format: Hardcover
  • Copyright: 2002-01-03
  • Publisher: Oxford University Press

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Summary

The muscular dystrophies are an important group of inherited disorders. They are characterized by muscle wasting and weakness, but vary considerably in their clinical manifestations and severity. This text reviews our understanding of the most important of these disorders. In many instances, the genes and protein products responsible for the dystrophies have been identified and it is now possible to establish a precise diagnosis, detect preclinical cases, identify carriers and offer prenatal dianostic testing. The book goes on to describe the opportunities for management of the symptoms through respiratory care, physiotherapy and surgical correction of contracture, and examines the potential, in the future, for effective treatment utilizing the new techniques of gene and cell therapy. Professor Emery has invited chapters from the leading international experts in the field providing a unique insight into the current situation and the hopes for the future.

Table of Contents

Preface ix
Contributors xi
Muscular dystrophy - an evolving concept
1(9)
Alan E. H. Emery
Congenital muscular dystrophies
10(29)
Eugenio Mercuri
Francesco Muntoni
Fukuyama congenital muscular dystrophy
39(16)
Kayoko Saito
Makio Kobayashi
Duchenne muscular dystrophy or Meryon's disease
55(17)
Alan E. H. Emery
Becker muscular dystrophy
72(23)
Marianne de Visser
Edo M. Hoogerwaard
Emery - Dreifuss muscular dystrophy
95(14)
Daniela Toniolo
The limb-girdle muscular dystrophies
109(28)
Katharine M. D. Bushby
Facioscapulohumeral muscular dystrophy
137(36)
Meena Upadhyaya
David N. Cooper
Distal muscular dystrophy
173(16)
Bjarne Udd
Hannu Somer
Oculopharyngeal muscular dystrophy: the muscular dystrophies
189(13)
Bernard Brais
Fernando M. S. Tome
Dilated cardiomyopathy and related cardiac disorders in muscular dystrophy
202(21)
J. Andoni Urtizberea
Denis Duboc
Ketty Schwartz
Gisele Bonne
Medical management and treatment of muscular dystrophy
223(24)
Adnan Y. Manzur
Respiratory care in muscular dystrophy
247(14)
Anita K. Simonds
Gene and cell therapy for primary myopathies
261(23)
Giulio Cossu
Paula R. Clemens
Surgical management of muscular dystrophy
284(13)
Luciano Merlini
Jurgen Forst
Animal models of muscular dystrophy
297(13)
Satoru Noguchi
Yukiko K. Hayashi
Index 310

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